Bis-PEG5-acid is a PEG linker containing two terminal carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
A dicarboxylic acid used in the preparation of potent dimeric inhibitors of the PSD-95-NMDA receptor interaction.
As a dicarboxylic acid, 4,7,10,13,16-Pentaoxanonadecanedioic Acid can be used in the preparation of potent dimeric inhibitors of the PSD-95-NMDA receptor interaction.
