This Menispermaceous alkaloid is found in the EtOH extract of Bornean Tino_x0002_miscium petiolare and crystallizes as colourless crystals from Me2CO. The 0-
methyl derivative is identical with (-)-Tetrahydropalmatine, m.p. 141-2°C.
A metabolite of the isoquinoline alkaloid biosynthesis pathway.
ChEBI: (S)-tetrahydrocolumbamine is a berberine alkaloid consisting of columbamine having four extra hydrogens at positions 5, 8, 13 and 13a and (S)-configuration. It is a berberine alkaloid and an organic heterotetracyclic compound. It is functionally related to a columbamine.
cAMP | Antifection | Dopamine Receptor
Tomita, Furukawa.,J. Pharm. Soc., Japan, 87,881 (1967)
