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Tetrahydroberberine

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Tetrahydroberberine Basic information
Tetrahydroberberine Chemical Properties
  • Melting point:166.5 °C
  • Boiling point:476.1±45.0 °C(Predicted)
  • Density 1.33±0.1 g/cm3(Predicted)
  • storage temp. Sealed in dry,Room Temperature
  • solubility DMSO: >10 mg/mL, soluble
  • form solid
  • pka6.53±0.20(Predicted)
  • color yellow
Safety Information
  • Hazard Codes Xn
  • Risk Statements 22
  • Safety Statements 36
  • WGK Germany 3
  • ToxicityLD50 in mice (mg/kg): 940 orally; 790 s.c.; 100 i.v. (Sadritdinov, Sultanov)
MSDS
Tetrahydroberberine Usage And Synthesis
  • UsesTetrahydroberberine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Tetrahydroberberine is used for treatment of degenerative diseases or conditions associated with KATP channel signaling.
  • UsesCanadine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Canadine is used for treatment of degenerative diseases or conditions associated with KATP channel signaling.
  • DefinitionChEBI: A berberine alkaloid that is 5,8,13,13a-tetrahydro-6H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline substituted by methoxy groups at positions 9 and 10.
Tetrahydroberberine(522-97-4)Related Product Information
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