Methyl maslinate (MM) (20-60 mg/kg; i.p.) shows significant, dose-dependent vasodepressor effect and sinus bradycardia, lasting more than 60 minutes with a maximum at 20 minutes, and shows potent hymodynamic effect[1].
Methyl maslinate (40 mg/kg) shows antidysrhythmic activity on ischemia-reperfusion dysrhythmia[1].
| Animal Model: | Wistar male rats (300-320 g)[1] |
| Dosage: | 20-60 mg/kg |
| Administration: | Intraperitoneal injection; once |
| Result: | Showed significant, dose-response vasodepressor effect and sinus bradicardia.
Antagonized β-Adrenergic.
Showed antidysrhythmic activity.
|
