brown to black iridescent crystalline powder
Ring opening of aziridines leading to sulfides and disulfides.1
Ammonium tetrathiomolybdate is used as an important reagent in synthetic chemistry and as a building block in bioinorganic chemistry. It is used in the treatment of copper toxicosis in animals and in Wilson's disease. It acts as a chelator in vivo to reduce copper levels. It interferes with angiogenesis and reduces tumor growth. Further, it is used in the synthesis of heterometallic sulfide clusters stabilized with dppm [bis(diphenylphosphino)methane] ligands. It is involved in the ring opening of aziridines leading to sulfides and disulfides.
reagent type: catalyst
core: molybdenum
Acts as a chelator in vivo to reduce copper levels. Tetrathiomolybdate interferes with angiogenesis and reduces tumor growth. Its mechanism may involve inhibition of NF-κB and downstream cytokines.
