酚嘧啶 扑蛲灵
酚嘧啶 扑蛲灵 性质
熔点 | >224°C (dec.) |
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储存条件 | Amber Vial, Refrigerator, Under inert atmosphere |
溶解度 | 可溶于DMSO(略微加热)、甲醇(略微加热) |
形态 | 固体 |
颜色 | 白色至类白色 |
InChIKey | WSYDAPQDBDVYIO-QEFJDTIGSA-N |
酚嘧啶 扑蛲灵 用途与合成方法
Antiparasitic
The activity of the veterinary drug Oxantel pamoate is studied against Trichuris muris , Ancylostoma ceylanicum and Necator americanus . An ED 50 s of 4.7 mg/kg is calculated for Oxantel pamoate against T. muris in mice. Combinations of Oxantel pamoate with pyrantel pamoate behaved antagonistically (combination index (CI)=2.53). Oxantel pamoate combined with Levamisole, Albendazole or Ivermectin using ratios based on their ED 50 s reveals antagonistic effects (CI=1.27, 1.90 and 1.27, respectively). A highly synergistic effect (CI=0.15) is observed when Oxantel pamoate-mebendazole is administered to T. muris -infected mice. Oxantel pamoate (10 mg/kg) lacks activity against Ancylostoma ceylanicum and Necator americanus .
酚嘧啶 扑蛲灵 价格(试剂级)
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
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2024-11-08 | HY-B1344 | 酚嘧啶 扑蛲灵 | 68813-55-8 | 100mg | 200 |
2024-11-08 | HY-B1344 | 酚嘧啶 扑蛲灵 | 68813-55-8 | 10mM * 1mLin DMSO | 220 |