奥克太尔 用途与合成方法
Oxantel (CP-14445) 是 Pyrantel (HY-12641) 的衍生物，是 N-亚型的 AChR 激动剂。Oxantel 是一种驱虫剂，具有优良驱虫活性。
nAChR
Oxantel ( 0.015-600 µg/mL; 24-72 hours) reduces the viability of
T. muris
.
Cell Viability Assay
| Cell Line: | T. muris |
| Concentration: | 0.015 µg/mL, 0.3 µg/mL, 0.6 µg/mL, 4.66 µg/mL, 9.375 µg/mL, 150 µg/mL, 600 µg/mL |
| Incubation Time: | 24 hours, 48 hours, 72 hours |
| Result: | Resulted in strongly reduced viabilities; resulted in strongly reduced viabilities within 24 hours but did not kill the worms. |
Oxantel (1-10 mg/kg; i.p.) displays a high activity against
T. muris
in vivo, with an EC
50
of 4.71 mg/kg.
Oxantel (10 mg/kg; i.p.) exhibits a worm burden reduction (WBR) of 92.5% and worm expulsion rate (WER) of 88.4% for
T. muris
.
| Animal Model: | 4 week-old female C57BL/10 mice and 3 week-old male |
| Dosage: | 1 mg/kg, 2.5 mg/kg, 5 mg/kg, 10 mg/kg |
| Administration: | Intraperitoneal injection |
| Result: | Inhibited T. muris in vivo. |
奥克太尔供应商 更多
陕西缔都医药化工有限公司
联系电话：029-029-029-81148696 18161915376
产品介绍：
中文名称：奥克太尔
英文名称：OXANTEL
CAS：36531-26-7
纯度：98%
包装信息：25KG;1KG;1KG
备注：业务负责人：王经理17391633967，微信同号；QQ 3257094746,固定电话029-81149305
TargetMol中国（陶术生物）
联系电话： 15002134094
产品介绍：
中文名称：奥克太尔
英文名称：Oxantel
CAS：36531-26-7
包装信息：25mg/RMB 10600
