C2 Dihydroceramide (13031-64-6) is a negative control for C2-ceramide (cat.# 10-1181).1,2 Induces autophagy in a variety of cell types.3,4
C2 DIHYDROCERAMIDE is White Solid
C2 DIHYDROCERAMIDE may be used as a negative control for C2 Ceramide
May be used as a negative control for C2 Ceramide.
ChEBI: A dihydroceramide in which the ceramide acyl group is specified as acetyl.
1) Bielawska et al. (1993) Selectivity of ceramide-mediated biology. Lack of activity of erythro-dihydroceramide; J. Biol. Chem. 268 26226
2) Obeid et al. (1993) Programmed cell death induced by ceramide; Science, 259 1769
3) Jiang et al. (2012) Gamma-tocotrienol induces apoptosis and autophagy in prostate cancer cells by increasing intracellular dihydrosphingosine and dihydroceramide; Int. J. Cancer, 130 685
4) Siddique et al. (2015) Dihydroceramides: From Bit Players to Lead Actors; J. Biol. Chem., 290 15371