Description
C2 Dihydroceramide (13031-64-6) is a negative control for C2-ceramide (cat.# 10-1181).1,2 Induces autophagy in a variety of cell types.3,4
References
[1] A. BIELAWSKA. Selectivity of ceramide-mediated biology. Lack of activity of erythro-dihydroceramide.[J]. The Journal of Biological Chemistry, 1993, 54 1: 26226-26232. DOI:
10.1016/s0021-9258(19)74304-x[2] LINA M. OBEID. Programmed Cell Death Induced by Ceramide[J]. Science, 1993, 259 5102. DOI:
10.1126/science.8456305[3] QING JIANG. Gamma-tocotrienol induces apoptosis and autophagy in prostate cancer cells by increasing intracellular dihydrosphingosine and dihydroceramide[J]. International Journal of Cancer, 2011, 130 3: 685-693. DOI:
10.1002/ijc.26054[4] MONOWARUL MOBIN SIDDIQUE. Dihydroceramides: From Bit Players to Lead Actors.[J]. The Journal of Biological Chemistry, 2015, 290 25: 15371-15379. DOI:
10.1074/jbc.r115.653204