Ac-AAVALLPAVLLALLAP-VAD-CHO (trifluoroacetate salt)

Ac-AAVALLPAVLLALLAP-VAD-CHO is a composite of Ac-VAD-CHO, a non-selective caspase inhibitor, and a cell-permeable hydrophobic sequence derived from K-FGF.1,2 It is a non-selective caspase inhibitor.3WARNING This product is not for human or veterinary use.

[1] JEE-YOUN KIM  Jae H P. ROS-dependent caspase-9 activation in hypoxic cell death[J]. FEBS Letters, 2003, 549 1-3: 94-98. DOI: 10.1016/s0014-5793(03)00795-6
[2] Y Z LIN. Inhibition of nuclear translocation of transcription factor NF-kappa B by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence.[J]. The Journal of Biological Chemistry, 1995, 270 24: 14255-14258. DOI: 10.1074/jbc.270.24.14255
[3] RITU RAJ KUMAR S A. Advances in Theranostic Nanomedicine: Integrating Diagnosis and Therapy for Precision Cancer Treatment.[J]. Current stem cell research & therapy, 2025. DOI: 10.2174/011574888x362719250603073728