LY2940094 (3, 10, or 30 mg/kg; orally daily for 4 days) dose-dependently reduces homecage ethanol self-administration in Indiana Alcohol-Preferring (P) and Marchigian Sardinian Alcohol-Preferring (msP) rats, without affecting food/water intake or locomotor activity[1].
| Animal Model: | Female Alcohol-Preferring (P) rats (250-320 g); Male Marchigian Sardinian Alcohol-Preferring (msP) rats (400-450 g)[1] |
| Dosage: | 3, 10, or 30 mg/kg |
| Administration: | P.o.; daily for 4 days |
| Result: | Reduced homecage ethanol self-administration.
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