4,16-Androstadien-3-beta-ol

Fasedienol (PH94B) is a neurochemical stimulator of the vomeronasal organ (VON). Fasedienol significantly increases Ca++. Fasedienol modulates the olfactory amygdala circuitry of fear and anxiety to alleviate symptoms of PMS and anxiety[1][2][3].

[1] Clive L. Jennings-White, et al. Steroids as neurochemical stimulators of the vno to alleviate symptoms of anxiety. Patent WO1998014194A1.
[2] Monti L, et al. Effect of fasedienol (PH94B) pherine nasal spray and steroidal hormones on electrogram responses and autonomic nervous system activity in healthy adult volunteers[J]. Human Psychopharmacology: Clinical and Experimental, 2024, 39(2): e2892. DOI:10.1002/hup.2892
[3] Monti L, et al. Neural circuits of anxiolytic and antidepressant pherine molecules. CNS Spectr. 2022 Feb;27(1):66-72. DOI:10.1017/S109285292000190X