cis-2-Dodecenoic acid, originally discovered in Burkholderia cenocepacia, can interfere with the bacterial quorum sensing system and inhibit bacterial biofilm formation and virulence factor production[1].
ChEBI: Cis-2-dodecenoic acid is the cis isomer of 2-dodecenoic acid.
Burkholderia cenocepacia produces a diffusible fatty acid signal molecule, cis-2-dodecenoic acid (BDSF), th at has been implicated in interspecies and interkingdom communication.
[1] Yinyue Deng, et al. Cis-2-dodecenoic acid signal modulates virulence of Pseudomonas aeruginosa through interference with quorum sensing systems and T3SS. BMC Microbiol. 2013 Oct 18;13:231. DOI:
10.1186/1471-2180-13-231