4,5-Dichloro-2-m-tolylpyridazin-3(2H)-one

Chemical Properties

Melting point	117 °C
Boiling point	339.6±52.0 °C(Predicted)
Density	1.39±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO: soluble10mg/mL (clear solutikon, warmed)
pka	-3.29±0.60(Predicted)
form	White solid
color	white to beige
InChI	1S/C11H8Cl2N2O/c1-7-3-2-4-8(5-7)15-11(16)10(13)9(12)6-14-15/h2-6H,1H3
InChIKey	SYUPLLHVMCLXEM-UHFFFAOYSA-N
SMILES	O=C1C(Cl)=C(Cl)C=NN1C2=CC=CC(C)=C2

Hazard Codes	T,Xi
Risk Statements	25-36
Safety Statements	26-45
RIDADR	UN 2811 6.1 / PGIII
WGK Germany	3
Storage Class	6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
Hazard Classifications	Acute Tox. 3 Oral Eye Irrit. 2

Animal Model:	5-week-old female CB17 SCID mice (MM.1S tumors volume=100 mm³)^[3]
Dosage:	20 mg/kg (diluted in saline)
Administration:	Intraperitoneal injections; treated on an every other day schedule for 14 days
Result:	Inhibited MM growth and prolongs host survival.