伏环孢素
伏环孢素 性质
| 沸点 | 1303.8±65.0 °C(Predicted) |
|---|---|
| 密度 | 1.016±0.06 g/cm3(Predicted) |
| 储存条件 | Store at -20°C |
| 溶解度 | 苯（微量）、甲醇（微量） |
| 酸度系数(pKa) | 13.32±0.70(Predicted) |
| 形态 | 固体 |
| 颜色 | 白色至类白色 |
伏环孢素 用途与合成方法
Calcineurin
This novel semi-synthetic calcineurin (CN) inhibitor is designated Voclosporin (ISATX247). The efficacy of Voclosporin as an immunosuppressive agent is examined using an in vitro calcineurin assay. Voclosporin (ISATX247) is a calcineurin inhibitor that has shown more potency than Cyclosporine in vitro.
All animals tolerate Voclosporin (ISATX247) and Cyclosporine A (CsA) very well. There are no severe adverse effects associated with either drug. In the Voclosporin group, all animals except 1 have diarrhea of different durations during the study (mean 2.3 days, range 2 to 7 days). This differs from the CsA and the control groups, where no animals have diarrhea. Mean weight loss at the end of the study is slightly higher in the Voclosporin group than in the CsA and control groups (3.4% vs 2.0% and 1.0%, respectively).
伏环孢素 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024-11-08 | HY-106638 | 1 mg | 1700 | ||
| 2024-11-08 | HY-106638 | Voclosporin | 515814-01-4 | 5mg | 4050 |
