UCCF-853 is an activator of the CFTR Cl- channel which may be useful for therapy of cystic fibrosis.
Uses
UCCF-853 is a CFTR modulator[1].
References
[1] Nicoletta Pedemonte, et al. Influence of cell background on pharmacological rescue of mutant CFTR. Am J Physiol Cell Physiol. 2010 Apr;298(4):C866-74. DOI:10.1152/ajpcell.00404.2009