二溴化-1,1ˊ-二庚基-4,4ˊ-联吡啶鎓
二溴化-1,1ˊ-二庚基-4,4ˊ-联吡啶鎓 性质
| 熔点 | 285 °C (dec.) (lit.) |
|---|---|
| 密度 | 1.2527 (rough estimate) |
| 折射率 | 1.6800 (estimate) |
| 储存条件 | Inert atmosphere,Room Temperature |
| 水溶解性 | Soluble in water |
| 形态 | 粉末晶体 |
| 颜色 | 淡黄色至琥珀色至深绿色 |
| CAS 数据库 | 6159-05-3(CAS DataBase Reference) |
| EPA化学物质信息 | 4,4'-Bipyridinium, 1,1'-diheptyl-, dibromide (6159-05-3) |
二溴化-1,1ˊ-二庚基-4,4ˊ-联吡啶鎓 用途与合成方法
DHBP inhibits the calcium release induced by 2 mM caffeine and 2 μg/mL polylysine with an IC 50 value of 5 μg/mL and 4 μg/mL, respectively. DHBP inhibits [ 3 H]-ryanodine binding in a dose-dependent manner with an IC 50 of 2.5 μg/mL and 90-100% inhibition at 20-30 μg/mL. Calcium uptake by SR is inhibited in the presence of caffeine and this inhibition is antagonized by concomitant addition of DHBP. Muscle twitches elicited by direct electrical muscle stimulation and contractions induced by either 10 mM caffeine or 1 fLM ryanodine are blocked by pretreatment with DHBP. DHBP blocks the calcium release from SR by direct interaction with the calcium release channel, also known as the ryanodine receptor.
二溴化-1,1ˊ-二庚基-4,4ˊ-联吡啶鎓 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024-01-25 | HY-101237 | 二溴化-1,1ˊ-二庚基-4,4ˊ-联吡啶鎓 | 6159-05-3 | 100mg | 500 |
| 2024-01-25 | HY-101237 | 二溴化-1,1ˊ-二庚基-4,4ˊ-联吡啶鎓 | 6159-05-3 | 10mM * 1mLin DMSO | 550 |
