Polysuccinimide

Polysuccinimide, an amorphous polymer, is a polyimide precursor. Polysuccinimide can be used for the production of degradable polymers[1].

Polysuccinimide is a biodegradable and tissue-friendly polymer derived from L-aspartic acid. Under physiological conditions (pH = 7.4), it hydrolyses to form water-soluble polyaspartic acid. As it can be readily modified with primary amines, it is possible to synthesise a variety of polysuccinimides and polyaspartic acids with diverse properties.

[1] Esmat Jalalvandi, et al. Polysuccinimide and its derivatives: Degradable and water soluble polymers (review). European Polymer Journal. Volume 109, December 2018, Pages 43-54.