Basic information Safety Related Supplier

CYCLO(-LEU-PRO)

Basic information Safety Related Supplier
CYCLO(-LEU-PRO) Basic information
CYCLO(-LEU-PRO) Chemical Properties
  • Melting point:163-165℃
  • Boiling point:427.6±34.0 °C(Predicted)
  • Density 1.14
  • storage temp. Inert atmosphere,2-8°C
  • pka13.27±0.40(Predicted)
CYCLO(-LEU-PRO) Usage And Synthesis
  • DescriptionCyclo(L-Leu-L-Pro) is a diketopiperazine metabolite that has been isolated from various bacterial and fungal species including Streptomyces. It is active against twelve strains of vancomycin-resistant enterococci (VRE) with MIC values of 12.5 μg/ml for E. faecalis strains K-99-34, K-00-184, and K-00-221. It also inhibits growth of K562, HL-60, and U937 leukemia cells in a concentration-dependent manner when used at concentrations of 1-500 μg/ml. Cyclo(L-Leu-L-Pro) also has antifouling activity, inhibiting attachment of B. amphitrite larva with an EC50 value of 0.15 mM.
  • Chemical PropertiesWhite Solid
  • UsesSorbicillin analog. A bioactive secondary metabolites from terrestrial Streptomyces species TN262.
  • DefinitionChEBI: A homodetic cyclic peptide composed from leucyl and prolyl residues.
CYCLO(-LEU-PRO)(2873-36-1)Related Product Information
CYCLO(-LEU-PRO)SupplierMore
  • Company Name:J & K SCIENTIFIC LTD.
  • Tel:400-666-7788 010-82848833-
  • Email:jkinfo@jkchemical.com;market6@jkchemical.com
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  • Company Name:GL Biochem (Shanghai) Ltd
  • Tel:13641803416 21-61263452-
  • Email:ymbetter@glbiochem.com;ymbetter@glbiochem.com
  •  
  • Company Name:Chemsky(shanghai)International Co.,Ltd.
  • Tel:021-50135380
  • Email:shchemsky@sina.com
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  • Company Name:ShenZhen InnoSyn Biotech Co.,Ltd
  • Tel:18503098468 0755-28351685
  • Email:innosyn@163.com
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  • Company Name:Bide Pharmatech Ltd.
  • Tel:400-1647117 021-61629020-8031
  • Email:sales@bldpharm.com;product07@bidepharm.com
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