L-半胱亚磺酸
L-半胱亚磺酸 性质
熔点 | >130°C (dec.) |
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沸点 | 492.8±55.0 °C(Predicted) |
密度 | 1.828±0.06 g/cm3(Predicted) |
储存条件 | −20°C |
溶解度 | 酸水溶液(微溶,超声处理),水(微溶) |
酸度系数(pKa) | 2.30±0.10(Predicted) |
形态 | 固体 |
颜色 | 白色至类白色 |
水溶解性 | Soluble to 100 mM in water |
L-半胱亚磺酸 用途与合成方法
mGluR1 3.92 (pEC 50 ) |
mGluR2 3.9 (pEC 50 ) |
mGluR4 2.7 (pEC 50 ) |
mGluR5 4.6 (pEC 50 ) |
mGluR6 4.0 (pEC 50 ) |
mGluR8 3.94 (pEC 50 ) |
Human Endogenous Metabolite
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L-Cysteinesulfinic acid is an endogenous agonist of a metabotropic receptor coupled to stimulation of phospholipase D (PLD) activity. L-CSA is an endogenous agonist of the PLD-coupled metabotropic excitatory amino acids (EAA) receptor. L-CSA selectively activates the PLD-coupled receptor. 1 mM L-CSA induces a significant increase in PLD activity in hippocampal slices, whereas 1 mM concentrations of L-glutamate, L-aspartate, and L-HCA are without effect. L-CSA elicits a dose-dependent increase in PLD activity in rat hippocampal slices in the presence of iGluR antagonists, with an approximate EC 50 of 500 uM. The PLD response induced by 1 mM L-CSA is not significantly decreased in the presence of 1 uM tetrodotoxin, suggesting that this response is not dependent upon L-CSA-induced increases in cell firing.
L-半胱亚磺酸 价格(试剂级)
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
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2024-11-08 | HY-100804 | 5 mg | 375 | ||
2024-11-08 | HY-100804 | 10 mg | 600 |