3'-Methoxy-2,2,2-trifluoroacetophenone

3’-Methoxy-2,2,2-Trifluoroacetophenone (cas# 30724-22-2) is a compound useful in organic synthesis.

Obtained by adding successively 1.6 M n-BuLi in hexane, then after 10 min, N,N-diethyltrifluoroacetamide (5 min) to a solution of 1-bromo-3-methoxybenzene in THF at 78° under argon and stirring the mixture for 2 h (88%).