(S)-(-)-5,5',6,6'-Tetramethyl-3,3'-di-tert-butyl-1,1'-biphenyl-2,2'-diol

Used as a ligand backbone for metathesis catalysts.
 2. Used as a ligand backbone in catalytic asymmetric hydrogenation.
 3. Used as a ligand backbone for asymmetric hydroformylation of allyl cyanide.
 4. Used as a ligand backbone for phosphoramidite ligands in the asymmetric
 Rh-catalyzed [2+2+2] cycloaddition.
 5. Used as a ligand backbone for the ring-opening polymerization of cyclic esters. 

• Cocatalyst in titanium-catalyzed intermolecular hydroamination

Reactant in preparation of:

• Sulfonate phenol ligands via sulfonylation
• Catalysts for asymmetric olefin hydroamination/cyclization reactions
• Single site catalyst precursors for catalysis of ring-opening reactions
• Biphen-Mo complex used for catalysis of enantioselective ring-closing metathesis

reagent type: ligand