N-Acetyl ACTH (1-17) (human) (trifluoroacetate salt)

N-Acetyl ACTH (1-17) is an N-terminal peptide fragment of adrenocorticotropic hormone (ACTH), a peptide hormone found in the brain that is involved in the biological stress response.1,2 It has been found in pituitary extracts from Cpefat/fat mice that lack the carboxypeptidase E active form, which is required for processing prohormones.3WARNING This product is not for human or veterinary use.

[1] FENGER M. alpha-Melanocyte-stimulating-hormone precursors in the pig pituitary.[J]. Biochemical Journal, 1986, 235 3: 715-722. DOI: 10.1042/bj2350715
[2] F L STRAND. Non-corticotropic ACTH peptides modulate nerve development and regeneration.[J]. Reviews in the Neurosciences, 1993, 4 4: 321-363. DOI: 10.1515/revneuro.1993.4.4.321
[3] FA-YUN CHE  Lloyd D F. Quantitative peptidomics of mouse pituitary: comparison of different stable isotopic tags[J]. Journal of Mass Spectrometry, 2005, 40 2: 238-249. DOI: 10.1002/jms.743