Basic information Safety Related Supplier

ACTINONIN

Basic information Safety Related Supplier
ACTINONIN Basic information
ACTINONIN Chemical Properties
  • Melting point:137-139°C
  • Density 1.139±0.06 g/cm3(Predicted)
  • storage temp. -20°C
  • pka9.19±0.20(Predicted)
  • form White to off-white powder.
  • BRN 1555250
  • CAS DataBase Reference13434-13-4(CAS DataBase Reference)
Safety Information
  • Safety Statements 22-24/25
  • WGK Germany 3
  • RTECS RG9900700
MSDS
ACTINONIN Usage And Synthesis
  • Chemical PropertiesOff-White Solid
  • Uses(-)-Actinonin is a bioactive peptide and antibiotic that is a potent inhibitor of aminopeptidase M and leucine aminopeptidase. Actinonin has observed to be an inhibitor of peptide deformylase, meprin A, and thermolysin. Actinonin also inhibits tumor cell invasion and matrix degradation along with displayed antitumor activity in vitro and in vivo as well as acting as an apoptotic inducer.
  • Uses
    Actinonin has been used as a control to inhibit meprin-β activity in C57BL/6 mice. It has also been used to study the high-affinity interaction of EcPDF with actinonin by 15N NMR spectroscopy and isothermal titration.
  • UsesA potent in vivo inhibitor of collagenase
  • General Description
    Chemical structure: peptide
  • Biochem/physiol ActionsActinonin has inhibitory action against peptide deformylase (PDF). It is effective against Gram-positive and fastidious Gram-negative microorganisms.
ACTINONIN(13434-13-4)Related Product Information
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