white to light yellow crystal powde
Isosorbide 5-Mononitrate is a metabolite of Isosorbide Dinitrate; used as an antianginal.
antidepressant, 5HT reuptake inhibitor
A metabolite of Isosorbide Dinitrate. Used as an antianginal
ChEBI: Isosorbide mononitrate is a nitrate ester and a glucitol derivative. It has a role as a nitric oxide donor and a vasodilator agent.
Imdur (Schering-Plough); Ismo (Dr. Reddy’s);
Monoket (Schwarz Pharma)
.
Isosorbide 5-mononitrate is a crystalline solid. Isosorbide 5-mononitrate is very flammable and may be toxic by ingestion.
The dinitrate, a heart drug, can detonate when dry, but is non explosive with 30% of water [J. Haz.. Mater., 1992, 32(1), 87]. The mononitrate would be expected to be less reactive.
Fire may produce irritating and/or toxic gases. Contact may cause burns to skin and eyes. Contact with molten substance may cause severe burns to skin and eyes. Runoff from fire control may cause pollution.
Flammable/combustible material. May be ignited by friction, heat, sparks or flames. Some may burn rapidly with flare burning effect. Powders, dusts, shavings, borings, turnings or cuttings may explode or burn with explosive violence. Substance may be transported in a molten form at a temperature that may be above its flash point. May re-ignite after fire is extinguished.
Vasodilator:
Treatment and prophylaxis of angina
Adjunct in congestive heart failure
