Oxothiazolidinecarboxylic acid treatment attenuates plantaris atrophy, restored glutathione levels, and increased catalase, Cu/Zn-SOD1, and Mn-SOD2 mRNA expression, but did not reduce other markers of oxidant stress or levels of these catabolic factors[1].
| Animal Model: | Male Sprague-Dawley rats (200-250 g, n= 6-7 rats/group)[1]. |
| Dosage: | 0.35% (w/v). |
| Administration: | Added to their diets at a concentration of 0.35% (w/v) for the final 12 wk. |
| Result: | Increased fiber CSAs compared to the non-supplemented, alcohol-fed group. |
