1-Palmityl-2-hydroxy-sn-glycero-3-PA (sodium salt)

1-Palmityl-2-hydroxy-sn-glycero-3-PA (sodium salt) is an ether analog of lysophosphatidic acid (LPA) containing a hexadecyl group at the sn-1 position.1 LPA binds to five different G protein-coupled receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.2,3WARNING This product is not for human or veterinary use.

[1] TAMOTSU TSUKAHARA. Different residues mediate recognition of 1-O-oleyllysophosphatidic acid and rosiglitazone in the ligand binding domain of peroxisome proliferator-activated receptor gamma.[J]. The Journal of Biological Chemistry, 2006, 281 6: 3398-3407. DOI: 10.1074/jbc.m510843200
[2] MOOLENAAR W H. LPA: a novel lipid mediator with diverse biological actions.[J]. Trends in Cell Biology, 1994, 4 6: 213-219. DOI: 10.1016/0962-8924(94)90144-9
[3] J. CHUN. International Union of Pharmacology. XXXIV. Lysophospholipid Receptor Nomenclature[J]. Pharmacological Reviews, 2002, 54 1: 265-269. DOI: 10.1124/pr.54.2.265