1,3-Dilinoleoyl-2-oleoyl-glycerol is a triacylglycerol that contains linoleic acid (Item Nos. 90150 | 90150.1 | 21909) at the sn-1 and sn-3 positions and oleic acid (Item Nos. 90260 | 24659) at the sn-2 position. It has been found in grape seed, pumpkin seed, soybean, sunflower, and wheat germ oils, with the highest content in grape seed oil.
1,3-Linolein-2-Olein, a triglyceride, is an antileishmanial agent. 1,3-Linolein-2-Olein inhibits promatigotes of the parasite (IC50=0.079 ug/ml) and inhibits the growth of amastigotes (IC50= 40.03 ug/ml)[1].
[1] Banchiwossen Bekele, et al. Evaluation of antileishmanial activities of triglycerides isolated from roots of Moringa stenopetala. Medicinal Chemistry Research volume 22, pages 4592–4599 (2013).
