Cyclopropene Cyanine 7 amine

Cy7 amine is a functionalized cyanine dye containing a free amine group, which can be conjugated with a variety of functionalities, including NHS esters, and epoxides. Cyanine7 is a far red dye ideal for live organism imaging and applications requiring low fluorescence background.

Appearance: Green solid
ex/em: 740/770 nm (MeOH/PBS)
Extinction coefficient (ε): 199000 Lmol1cm1
Quantum yield (Φ): 0.3

Cyanine 7-amine (chloride hydrochloride) can be used to label cationic nanoparticles (NPs) or to NP conjugates (NPCs). It can track the residence time and clearance of nanoparticles in the body[1].

[1] Melgar-Asensio I, et al. Extended Intravitreal Rabbit Eye Residence of Nanoparticles Conjugated With Cationic Arginine Peptides for Intraocular Drug Delivery: In Vivo Imaging. Invest Ophthalmol Vis Sci. 2018 Aug 1;59(10):4071-4081. DOI:10.1167/iovs.18-24087