Cy7 carboxylic acid is a free non-activated NIR (near-infraed fluorescent) dye. It is a non-sulfonated reagent with good solubility in organic solvents and limited aquous solubility.
Cyanine7 carboxylic acid chloride belongs to the cyanine dye series and is a common fluorescent marker for biomolecules that can interact with biomolecules. Cyanine dyes may also bind to double-helical DNA through intercalation and exhibit enhanced fluorescence upon binding.
[1] Armitage B A. Cyanine dye–DNA interactions: intercalation, groove binding, and aggregation[J]. DNA Binders and Related Subjects: -/-, 2005: 55-76.
