TRISODIUM 2-METHYLCITRATE, RACEMIC MIXTURE OF DIASTEREOMERS
TRISODIUM 2-METHYLCITRATE, RACEMIC MIXTURE OF DIASTEREOMERS
TRISODIUM 2-METHYLCITRATE, RACEMIC MIXTURE OF DIASTEREOMERS 性质
| 储存条件 | Store at -20°C |
|---|---|
| 形态 | 固体 |
| 颜色 | 白色至米白色 |
| InChI | 1S/C7H10O7.3Na/c1-3(5(10)11)7(14,6(12)13)2-4(8)9;;;/h3,14H,2H2,1H3,(H,8,9)(H,10,11)(H,12,13);;;/q;3*+1/p-3 |
| InChIKey | HPLKAWNRQOHUKD-UHFFFAOYSA-K |
| SMILES | [Na+].[Na+].[Na+].CC(C([O-])=O)C(O)(CC([O-])=O)C([O-])=O |
TRISODIUM 2-METHYLCITRATE, RACEMIC MIXTURE OF DIASTEREOMERS 用途与合成方法
|
Human Endogenous Metabolite
|
2-Methylcitric acid trisodium impairs glutamate metabolism and induces permeability transition in brain mitochondria.
2-Methylcitric acid trisodium inhibits glutamate dehydrogenase (GDH) activity at concentrations as low as 0.5 mM.
2-Methylcitric acid trisodium (1 mM, 3 mM; 150 seconds) provokes a significant decrease in mitochondrial membrane potential and induced swelling in Ca
2+
-loaded mitochondria supported by different substrates.
2-Methylcitric acid trisodium behaves as a potent inhibitor of glutamate oxidation by inhibiting glutamate dehydrogenase activity and as a permeability transition inducer, disturbing mitochondrial energy homeostasis.
2-Methylcitric acid trisodium does not significantly impair mitochondrial glutamate transport.
2-Methylcitric acid trisodium does not significantly impair glutamate mitochondrial transport in liver mitochondria.
TRISODIUM 2-METHYLCITRATE, RACEMIC MIXTURE OF DIASTEREOMERS 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2025-12-22 | HY-113371A | 117041-96-0 | 1 mg | 1250 | |
| 2025-12-22 | HY-113371A | TRISODIUM 2-METHYLCITRATE, RACEMIC MIXTURE OF DIASTEREOMERS | 117041-96-0 | 5mg | 3500 |
