TRISODIUM 2-METHYLCITRATE, RACEMIC MIXTURE OF DIASTEREOMERS
TRISODIUM 2-METHYLCITRATE, RACEMIC MIXTURE OF DIASTEREOMERS
TRISODIUM 2-METHYLCITRATE, RACEMIC MIXTURE OF DIASTEREOMERS 用途与合成方法
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Human Endogenous Metabolite
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2-Methylcitric acid trisodium impairs glutamate metabolism and induces permeability transition in brain mitochondria.
2-Methylcitric acid trisodium inhibits glutamate dehydrogenase (GDH) activity at concentrations as low as 0.5 mM.
2-Methylcitric acid trisodium (1 mM, 3 mM; 150 seconds) provokes a significant decrease in mitochondrial membrane potential and induced swelling in Ca
2+
-loaded mitochondria supported by different substrates.
2-Methylcitric acid trisodium behaves as a potent inhibitor of glutamate oxidation by inhibiting glutamate dehydrogenase activity and as a permeability transition inducer, disturbing mitochondrial energy homeostasis.
2-Methylcitric acid trisodium does not significantly impair mitochondrial glutamate transport.
2-Methylcitric acid trisodium does not significantly impair glutamate mitochondrial transport in liver mitochondria.
TRISODIUM 2-METHYLCITRATE, RACEMIC MIXTURE OF DIASTEREOMERS 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024-11-08 | HY-113371A | 1 mg | 1250 | ||
| 2024-11-08 | HY-113371A | TRISODIUM 2-METHYLCITRATE, RACEMIC MIXTURE OF DIASTEREOMERS | 117041-96-0 | 5mg | 3500 |
