CGP 54626 is a selective antagonist of the GABAB receptor with an IC50 value of 4 nM. It can be used to investigate the role of GABAB receptors in neurological signaling.
CGP 54626 (hydrochloride) is a selective antagonist of GABAB receptor with an IC50 value of 4 nM. CGP 54626 (hydrochloride) can be used to investigate the role of GABAB receptors in neurological signaling[1].
A potent, selective GABA B receptor antagonist (IC 50 = 4 nM).
[1] Kaupmann K, et al. GABA(B)-receptor subtypes assemble into functional heteromeric complexes. Nature. 1998 Dec 17;396(6712):683-7. DOI:
10.1038/25360