N,N,N',N'-Tetramethyl-O-(N-succinimidyl)uronium hexafluorophosphate

White to off-white crystalline powder

Coupling reagent for peptide synthesis and the formation of other amides. Reactant for synthesis of liposomal contrast agents for magnetic resonance imaging, synthesis of protein labeling molecules, synthesis of thiol-reactive Cy5 derivatives.

Coupling reagent for peptide synthesis and the formation of other amides. Yield in aqueous solution is excellent too.

N,N,N′,N′-Tetramethyl-O-(N-succinimidyl)uronium hexafluorophosphate can be used to prepare N-succinimidyl 4-[¹⁸F]fluorobenzoate ([¹⁸F]-SFB), a prosthetic group for the fluorination of biomolecules for PET imaging.