5,7-Dimethoxycoumarin

photosensitizing agent

5,7-Dimethoxycoumarin is a derivitized coumarin compound.

ChEBI: 5,7-dimethoxy-1-benzopyran-2-one is a member of coumarins.

Journal of the American Chemical Society, 118, p. 6305, 1996 DOI: 10.1021/ja961107i

5,7-dimethoxycoumarin is isolated and identified from leaves and fruits of Pelea anisata H. Mann, a plant whose fruit are used in the construction of mohikana leis. It induces frameshift mutagenesis in bacteria. It also causes lethal photosensitization and the formation of sister chromatid exchanges in Chinese hamster cells.

5,7-Dimethoxycoumarin induces the processes of differentiation and melanogenesis in murine (B16) and human (A375).