(4E)-1,7-双(3,4-二羟基苯基)-4-庚烯-3-酮
(4E)-1,7-双(3,4-二羟基苯基)-4-庚烯-3-酮
(4E)-1,7-双(3,4-二羟基苯基)-4-庚烯-3-酮 性质
| 沸点 | 622.0±55.0 °C(Predicted) |
|---|---|
| 密度 | 1.313±0.06 g/cm3(Predicted) |
| 储存条件 | -20°C |
| 酸度系数(pKa) | 9.76±0.10(Predicted) |
| 形态 | 油状物 |
| 颜色 | 米白色至浅棕色 |
| 主要应用 | 代谢组学 维生素、营养保健品和天然产品 |
| InChI | 1S/C19H20O5/c20-15(8-5-14-7-10-17(22)19(24)12-14)4-2-1-3-13-6-9-16(21)18(23)11-13/h2,4,6-7,9-12,21-24H,1,3,5,8H2/b4-2+ |
| InChIKey | VWHYFMQKJYFLCC-DUXPYHPUSA-N |
| SMILES | Oc1ccc(CC\C=C\C(=O)CCc2ccc(O)c(O)c2)cc1O |
(4E)-1,7-双(3,4-二羟基苯基)-4-庚烯-3-酮 用途与合成方法
Hirsutenone (0-100 μM; 48 hours) inhibits adipogenesis in 3T3-L1 preadipocytes and exhibits non-toxicity at 20-100 μM. Hirsutenone (0-100 μM; 48 hours) attenuates MDI-induced lipid accumulation in 3T3-L1 preadipocytes in a dose-dependent manner. In particular, HST at 40 and 80 μM significantly reduces MDI-induced adipogenesis in 3T3-L1 preadipocytes.Hirsutenone (0-100 μM; 48 hours) reduces the protein expression levels of PPARg, C/EBPa, and FAS in a dose-dependent manner in 3T3-L1 preadipocytes.Hirsutenone (80 μM; 20-24 hours) suppresses the cell cycle entry to S and G2/M phases occurrs at 20 hours when compares with at 20 hours. At 24 h, more cells are arrested in G1 phase (53% of total cells) when compares with the MDI-induced group which contains the majority of cells (56% of total cells) in G2/M phase.
安全信息
| 危险品标志 | N |
|---|---|
| 危险类别码 | 50 |
| 安全说明 | 61 |
| 危险品运输编号 | UN 3077 9 / PGIII |
| WGK Germany | 3 |
| 存储类别 | 11 - 可燃固体 |
| 危险性类别 | 危害水生环境-急性危害 类别1 危害水生环境-长期危害 类别1 |
(4E)-1,7-双(3,4-二羟基苯基)-4-庚烯-3-酮 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026-09-15 | HY-N4042 | (4E)-1,7-双(3,4-二羟基苯基)-4-庚烯-3-酮 | 41137-87-5 | 1 mg | 2450 |
| 2023-03-20 | HY-N4042 | (4E)-1,7-双(3,4-二羟基苯基)-4-庚烯-3-酮 | 41137-87-5 | 5 mg | 13000 |
