Basic information Safety Related Supplier
ChemicalBook >  Product Catalog >  Chemical Reagents >  Organic reagents >  Thiolate >  (2-MERCAPTOETHYL)TRIMETHYLSILANE


Basic information Safety Related Supplier
  • Boiling point:144-146 °C(lit.)
  • Density 0.839 g/mL at 25 °C(lit.)
  • refractive index n20/D 1.454(lit.)
  • Flash point:85 °F
  • storage temp. 2-8°C
  • solubility Soluble in MeOH, CH2Cl2, THF, and most organic solvents.
  • BRN 1732126
Safety Information
  • Hazard Codes Xi
  • Risk Statements 10-36/37/38
  • Safety Statements 26-36
  • RIDADR UN 1993 3/PG 3
  • WGK Germany 3
  • RTECS KJ2621000
  • 13
  • HazardClass 3.2
  • PackingGroup III
  • Physical propertiesbp 144–146 °C [52–54 °C (25 Torr)]; d 0.850.
  • Uses2-(Trimethylsilyl)ethanethiol is a reagent used as a monoprotected sulfide dianion equivalent for the two-step installation of a divalent sulfur atom into organic molecules. It participates in the reactions of Thiol Substitution Reactions, Source of Sulfur Acid Derivatives, etc.
  • PreparationThe high commercial cost of 2-(trimethylsilyl)ethanethiol necessitates methods for its lab scale synthesis. The radical addition of thiolacetic acid to vinyltrimethylsilane occurs thermally to afford a 9:1 ratio of regioisomers, the 1- and 2-(trimethylsilyl)ethyl thiolesters of acetic acid (eq 1). Photochemical initiation may improve the ratio of regioisomers obtained. Purification of the thiolacetate by careful fractional distillation should be performed prior to conversion to the thiol in order to ensure high purity. The conversion to thiol is best performed with LAH3 or methanolic K2CO3, but ammonolysis may also be suitable. Saponification with KOH in water/ethanol is slightly less efficient. Direct radical addition of liquid H2S to vinyl trimethylsilane has been demonstrated, but the procedure is low-yielding and inconvenient.

(2-MERCAPTOETHYL)TRIMETHYLSILANE(18143-30-1)Related Product Information
  • Company Name:Energy Chemical
  • Tel:400-005-6266 021-58432009-
  • Company Name:Shanghai Hanhong Scientific Co.,Ltd.
  • Tel:021-54302127 021-54306202-
  • Company Name:Syntechem Co.,Ltd
  • Tel:Please Email
  • Company Name:BEST-REAGENT
  • Tel:18981987031 400-1166-196
  • Company Name:Chengdu Ai Keda Chemical Technology Co., Ltd.
  • Tel:4008-755-333 028-85911938-