A reagent used in the synthesis of quaternary chiral prolines
Structure-mutagenic activity relationships in the Salmonella typhimurium TA100 strain in a series of short-chain halogenated hydrocarbons and alcohols.
3-Bromo-1-propanol is used in the synthesis of fluorescent halide-sensitive quinolinium dyes, chiral, quaternary prolines through cyclization of quaternary amino acids and molten salt-polymers. It is utilized for the study of micellar media and in microemulsions based on cationic or a nonionic surfactant by reacting with phenols. It acts as a grafting agent in the synthesis of recyclable reagents and an intermediate in the synthesis of organic molecules.
ChEBI: 3-Bromo-1-propanol is a primary alcohol.
Highly flammable. Water soluble.
3-Bromo-1-propanol may be sensitive to prolonged exposure to light.
3-Bromo-1-propanol is combustible.
3-Bromo-1-propanol can be synthesized from 3-bromopropionic acid or methyl 3-bromopropionate using lithium aluminum hydride-aluminum chloride[1].
[1] Nystrom, R. F. (1959). Reduction of Organic Compounds by Mixed Hydrides. III. 3-Bromopropionic Acid, 3-Bromopropionyl Chloride, Methyl 3-Bromopropionate and Halides. Journal of the American Chemical Society, 81(3), 610–612.
https://doi.org/10.1021/ja01512a026
