6-bromo-2-chloroquinoxaline

6-Bromo-2-chloroquinoxaline can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

55687-34-8

55687-02-0

C. Synthesis of 6-bromo-2-chloroquinoxaline. 6-Bromoquinoxalin-2(1H)-one (255 mg, 1.1 mmol) from Step B was added to a reaction flask containing phosphorus trichloride (3.4 ml, 36.5 mmol). The reaction mixture was stirred and reacted at 60 °C overnight. After completion of the reaction, the mixture was cooled to room temperature and the reaction was quenched by slowly pouring into ice water. The precipitated solid was collected by filtration and dried to give the target product 6-bromo-2-chloroquinoxaline (239 mg, 87% yield).