Light yellow needle-shaped crystals, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Radix Angelicae Pubescentis.
GABA receptor antagonist, phototoxin
ChEBI: Pimpinellin is a furanocoumarin.
Pimpinellin is a coumarin isolated from roots of Angelica dahurica and Zosima absinthifolia th at exhibits anti-tumor, anti-allergic, antioxidant and anticholinesterase activities. It appears to reduce the release of histamine, secretion of TBF-α, interleukin (IL)-1β and IL-4. Pimpinellin exhibits potent cytotoxic activities against MGC-803, PC3, and A375 cancer cell lines.