米帕明
中文名称:米帕明
英文名称:IMIPRAMINE
CAS号:50-49-7
分子式:C19H24N2
分子量:280.41
EINECS号:200-042-1
Mol文件:50-49-7.mol
米帕明 性质
| 熔点 | 174°C |
|---|---|
| 沸点 | bp0.1 160° |
| 密度 | 0.9935 (rough estimate) |
| 折射率 | 1.5640 (estimate) |
| 酸度系数(pKa) | pKa 9.66(H2O,t = 25,I=0.025) (Uncertain) |
| 形态 | 液体 |
| 颜色 | 无色至浅黄 |
| 水溶解性 | 18.23mg/L(24 ºC) |
| Solvent | Ethanol under nitrogen |
| Concentration | 1 mCi/ml |
| Specific Activity | 60-90 Ci/mmol |
| BCS Class | 1 |
| EPA化学物质信息 | Imipramine (50-49-7) |
安全信息
| 毒害物质数据 | 50-49-7(Hazardous Substances Data) |
|---|---|
| 毒性 | A tertiary amine tricyclic antidepressant that is thought to exert its therapeutic effect by inhibiting the reuptake of serotonin and norepinephrine centrally. A major metabolite is N-desmethylimipramine (desipramine), also used as an antidepressant drug. Desipramine differs from imipramine in being a better blocker of norepinephrine, rather than serotonin, uptake. Side effects, including sedation and drowsiness, dry mouth, urinary retention, constipation, and orthostatic hypotension, are probably due to the anticholinergic, anti-α-adrenergic, and antihistaminergic receptor-blocking properties. Imipramine should not be used in conjunction with a monoamine oxidase inhibitor or other treatment that increases catecholamine concentrations (e.g., drugs containing sympathomimetic amines). Imipramine should be avoided in patients with cardiovascular disease or seizure disorder, or in those who may abuse alcohol, as imipramine lowers seizure threshold, can produce cardiovascular toxicity and may potentiate the effects of alcohol. Imipramine intoxication can include CNS abnormalities (e.g., drowsiness, stupor, coma, and extrapyramidal symptoms), cardiac arrhythmia, and respiratory depression. Children appear to be particularly vulnerable to the cardiotoxic and seizure-inducing effects of high doses of imipramine. The oral LD50 in female rats is 305 mg/kg. |
米帕明 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024-11-11 | XW5049702 | 米帕明 | 50-49-7 | 1G | 2530 |
| 2024-11-08 | HY-B1490A | 5 mg | 650 |
米帕明供应商 更多
北京百灵威科技有限公司
联系电话：010-82848833 400-666-7788
产品介绍：
中文名称：盐酸丙咪嗪
英文名称：IMipraMine hydrochloride
CAS：50-49-7
纯度：>97%
包装信息：10Mg,1Mg,5Mg
备注：化学试剂、精细化学品、医药中间体、材料中间体
上海鑫圭生物科技有限公司
联系电话： 17501653715
产品介绍：
中文名称：盐酸丙咪嗪
英文名称：3-(10,11-Dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine
CAS：50-49-7
纯度：95%
包装信息：10g,25g,50g,100g,250g,500g,1kg,5kg……
江苏艾康生物医药研发有限公司
联系电话：025-66113011 18112977050
产品介绍：
英文名称：3-(10,11-Dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine
CAS：50-49-7
纯度：95+%
包装信息：1g;5g;10g
上海丸全化学科技有限公司
联系电话：021-57171708; 18721745940
产品介绍：
中文名称：米帕明
英文名称：3-(10,11-Dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine
CAS：50-49-7
纯度：95%+
包装信息：50g;100g;250g
