(Chloromethyl)triphenylphosphonium chloride

white to almost white fine crystalline powder

Used for corrosion inhibition of iron

Reactant involved in:

• Acting as a potential electrophile
• Elimination reactions for the synthesis of linear alkynes
• Intramolecular nucleophilic vinylic substitution
• Homologation of aldehydes
• Endo-selective alkynol cycloisomerization

(Chloromethyl)triphenylphosphonium Chloride is a Wittig reagent.

(Chloromethyl)triphenylphosphonium chliride is available commercially (chloride or iodide salt) or synthetically from Triphenylphosphine and Chloroiodomethane.

(Chloromethyl)triphenylphosphonium chliride is a precursor to the chloro-substituted ylide for Wittig reactions with aldehydes and ketones to form 1-chloroalkenes and, after elimination of HCl, terminal alkynes.

reaction type: C-C Bond Formation

For best results the anhydrous salt should be used. The ylide, formed from the salt and strong base, will react with air, water, or other acidic protons