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Exifone

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Exifone Basic information
Exifone Chemical Properties
  • Melting point:245°C
  • Boiling point:674.6±55.0 °C(Predicted)
  • Density 1.759±0.06 g/cm3(Predicted)
  • pka6.99±0.40(Predicted)
  • Merck 3915
  • CAS DataBase Reference52479-85-3(CAS DataBase Reference)
Safety Information
  • Risk Statements 36/37/38
  • Safety Statements 26-36
  • RTECS PC4995000
  • ToxicityLD50 in rats (g/kg): 0.355 i.p.; 1.425 orally (Gazave)
MSDS
Exifone Usage And Synthesis
  • DescriptionExifone is a nootropic indicated for the treatment of cognitive dysfunctions in geriatric patients. Its reported clinical efficacy is ascribed to pharmacological activities including activation of neuronal oxygen and glucose metabolism, free radical scavenging, and indirect effects on serotonergic and dopaminergic pathways.
  • Chemical Propertiesyellow amorphous powder
  • OriginatorPharmascience (France)
  • UsesExifone is a nootropic drug and cognitive enhancing agent. Exifone is a free radical scavenger shown to have protective effects againts Exifone has been shown to antagonize amnesias induced by benzodiazepines in mice.
  • PreparationPreparation by condensation of gallic acid with pyrogallol,
    ? in the presence of zinc chloride at 120° (good yield) or at 145° for 3 h (Nencki reaction);
    ? in the presence of zinc chloride and phosphorous oxychloride at 80° for 2 h, via Fries rearrangement.
  • brand nameAdlone
Exifone Preparation Products And Raw materials
Exifone(52479-85-3)Related Product Information
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