ChemicalBook Product Catalog API Antiparasitic drugs Anthelmintics PIPERAZINE ADIPATE

PIPERAZINE ADIPATE

Product NamePIPERAZINE ADIPATE
CAS142-88-1
MFC10H20N2O4
MW232.28
EINECS205-569-0
MOL File142-88-1.mol

Chemical Properties

Melting point	256-257°
Boiling point	374.44°C (rough estimate)
Density	1.1633 (rough estimate)
vapor pressure	2.8hPa
refractive index	1.4710 (estimate)
storage temp.	Store at -20°C
solubility	571.42mg/L in organic solvents at 20 ℃
form	Solid
pka	0[at 20 ℃]
color	White to Almost white
Odor	at 100.00?%. odorless
Water Solubility	almost transparency
Merck	14,7465
Stability	Stable. Combustible. Incompatible with strong oxidizing agents. May be light-sensitive.
Major Application	pharmaceutical (small molecule)
InChI	1S/C6H10O4.C4H10N2/c7-5(8)3-1-2-4-6(9)10;1-2-6-4-3-5-1/h1-4H2,(H,7,8)(H,9,10);5-6H,1-4H2
InChIKey	BVEGEKOBSPXUJS-UHFFFAOYSA-N
SMILES	C1CNCCN1.OC(=O)CCCCC(O)=O
LogP	-0.522 at 28℃
CAS DataBase Reference	142-88-1(CAS DataBase Reference)
EPA Substance Registry System	Piperazine adipate (1:1) (142-88-1)

Safety Information

RIDADR	UN 2579 8 / PGIII
WGK Germany	WGK 1
RTECS	MO1955000
TSCA	TSCA listed
HS Code	2933599550
Storage Class	11 - Combustible Solids
Toxicity	LD50 in mice, rats (g/kg): 11.4, 7.9 orally (Cross)

Usage And Synthesis

Chemical Properties

white crystals or powder

Uses

It is used as an anthelmintic for humans and farm animals against intestinal roundworms and pinworms infection

Uses

Piperazine Adipate is used as an anthelmintic agent. Derivatives of piperazine are widely used in the pharmaceutical, biomedical and chemical fields. Piperazine derivatives are known to have high antiserotonin potency, antimicrobial activity, and potential anticancer activity in humans.

Definition

ChEBI: Piperazine adipate is a piperazinium salt obtained by combining equimolar amounts of piperazine and adipic acid. It has a role as an anthelminthic drug and an antinematodal drug. It contains an adipate(2-) and a piperazinium(2+).

General Description

Odorless white crystalline powder or solid. Slightly acid taste. Melting point 256-257°C. Dissolves slowly. pH (0.2-0.01 molar aqueous solutions) 5.45. pH (5% solution) 5 - 6.

Air & Water Reactions

Water soluble.

Reactivity Profile

PIPERAZINE ADIPATE gives weakly acidic aqueous solutions. Can serve as both an oxidizing agent and as a reducing agent.

Fire Hazard

Flash point data for PIPERAZINE ADIPATE are not available; however PIPERAZINE ADIPATE is probably combustible.

Flammability and Explosibility

Non flammable

PIPERAZINE ADIPATE Supplier

PIPERAZINE ADIPATE manufacturers

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