White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the rhizome of Glycyrrhiza uralensis Fisch.
Licochalcone E, a flavonoid compound isolated from Glycyrrhiza uralensis, inhibits NF-κB and AP-1 transcriptional activity through the inhibition of AKT and MAPK activation[1].
Licochalcone E, a flavonoid extracted from Glycyrrhiza inflate, inhibits the transcriptional activity of NF-κB and AP-1 by inhibiting the activation of AKT and MAPK.
[1] Lee HN, et al. Mechanisms by which licochalcone e exhibits potent anti-inflammatory properties: studies with phorbol ester-treated mouse skin and lipopolysaccharide-stimulated murine macrophages. Int J Mol Sci. 2013 May 24;14(6):10926-43. DOI:
10.3390/ijms140610926
