Trofinetide is a synthetic analogue of the endogenous N-terminus tripeptide, Glycine-Proline-Glutamate (GPE), that has shown to be neuroprotective in animal models of brain injury.
ChEBI: Alisporivir is a homodetic cyclic peptide. It has a role as an anticoronaviral agent.
Alisporivir is a Cyclophilin A inhibitor with potent anti-hepatitis C virus (HCV) activity. Alisporivir has also been investigated for Duchenne muscular dystrophy.
Combination treatment with Alisporivir and ICN-1229 does not protect against SARS-CoV infection in a mouse model[3].