One of the alkaloids isolated from the leaves of Mitragyna speciosa, the structure
of the base has been determined from the NMR spectrum which demonstrates
that the alkaloid has a cis DIE ring junction and a conformation such that the
oxindole ring deshields the ester methoxyl group.
Uncarine D is a compound extracted from Uncaria tomentosa leaves. The compounds extracted from these leaves have exhibited immunomodulating, antiinflammatory and anti-cancer activity, attributed to the presence of tetra/pentacyclic oxindole alkaloids.
ChEBI: Uncarine D is a member of indolizines.
Beckett et al., Sci. Pharm., Froc., 25th (1965)
