Bis(trimethylsilyl) malonate

clear colorless to straw colored liquid

Bis(trimethylsilyl) malonate was used as cyclocondensation agent in cyclocondensation reactions. It was also used in the preparation of β-keto acids and methyl ketones.

Bis(trimethylsilyl) malonate is precursor for metal-organic chemical vapor deposition (MOCVD) of HfO₂ and ZrO₂ thin films. It undergoes acylation reaction with acid chlorides and acyl carbonates in the presence of triethylamine and magnesium or lithium salts to give β-keto acids or methyl ketones.

Bis(trimethylsilyl) Malonate can be easily prepared from malonic acid by a number of silylation procedures. It is a reagent useful in the synthesis of β-keto acids and methyl ketones.

[1] Tetrahedron, 2016, vol. 72, # 37, p. 5713 - 5723
[2] Canadian Journal of Chemistry, 1972, vol. 50, p. 3913 - 3916