头孢三唑
中文名称:头孢三唑
英文名称:Cefetrizole
CAS号:65307-12-2
分子式:C16H15N5O4S3
分子量:437.52
EINECS号:
Mol文件:65307-12-2.mol
头孢三唑 用途与合成方法
Ceftezole 是一种 α-Glucosidase 抑制剂,其 IC50 和 Ki 值分别为 2.1 μM 和 0.578 μM。
IC50: 2.1 μM (α-Glucosidase)
Ki: 0.578 μM (α-Glucosidase)
In in vitro α-Glucosidase assays, Ceftezole is shown to be a reversible, non-competitive inhibitor of yeast α-glucosidase with a K i value of 5.78×10 -7 M when the enzyme mixture is pretreated with ceftezole.
Using an in vivo streptozotocin-induced mouse model, blood glucose levels are confirmed to be decreased by 30% 20 min after Ceftezole treatment (10 mg/kg/day). Expression levels of glycogen synthase kinase-3, peroxisome proliferator-activated receptor-γ, and uncoupling protein-3 mRNA are also slightly decreased compare to controls following Ceftezole treatment.
头孢三唑供应商 更多
TargetMol中国(陶术生物)
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产品介绍:
中文名称:头孢三唑
英文名称:Cefetrizole;Cefetrizole
CAS:65307-12-2
纯度:98%
包装信息:5 mg