2-Furanmethanamine, N-butyl-5,5-bis(4-fluorophenyl)tetrahydro-, hydrochloride (1:1)

LY393615 (NCC1048) is a novel neuronal Ca2+ (calcium channel) and Na + channel (sodium channel) blocker with IC50s of 1.9 μΜ and 5.2 μΜ for α1A and α1B calcium channel subunits. LY393615 has good brain penetration and neuroprotective effects in models of in cerebral ischemia that can be used for neurological disease research[1].

P/Q-type calciumchannel: 4 μM (IC₅₀)

[1] O'Neill MJ, et.al. LY393615, a novel neuronal Ca(2+) and Na(+) channel blocker with neuroprotective effects in models of in vitro and in vivo cerebral ischemia. Brain Res. 2001 Jan 5;888(1):138-149. DOI:10.1016/s0006-8993(00)03043-2