Sodium prop-2-yne-1-sulfonate has a variety of uses, primarily as an organic synthetic material and as an experimental buffer. It is also used in the preparation of a complex nickel plating solution. In bright nickel plating, it is an auxiliary alignment agent, which improves the brightness and filler of the lower zones, with obvious effects and less brittle plating. In addition, the compound is useful in various biochemical and physiological studies due to its ability to bind to proteins and other molecules.